Delta 8 THC, a hemp derivative, has gained popularity as a cannabinoid with mild psychoactive effects. It offers numerous benefits by interacting with cannabinoid receptors in the body, stimulating essential physiological processes. This federally legal compound does not require a prescription, distinguishing it from medical marijuana. However, it’s crucial to be aware of potential interactions between delta 8 THC and prescription medications before incorporating it into your routine.
The CYP3A4 Enzyme and Delta 8 THC
Concerns have arisen regarding possible interactions between delta 8 THC products and prescription drugs due to the cannabinoid’s relationship with the metabolite CYP3A4. The CYP3A4 enzyme plays a crucial role in metabolizing approximately half of all available drugs, including benzodiazepines, opioids, NSAIDs, and corticosteroids, among others.
Delta 8 THC as a CYP3A4 Inhibitor
Delta 8 THC, along with various other cannabinoids found in CBD products, acts as a CYP3A4 inhibitor. This means that it reduces the levels of CYP3A4 in the body, potentially leading to interactions with certain medications. When CYP3A4 levels are inhibited, drugs may not be metabolized effectively, resulting in their accumulation in the body. Each subsequent dose of the medicine adds to the concentration of unmetabolized substances, increasing the risk of an overdose.
Understanding the Risks
The accumulation of drugs in the bloodstream due to inhibited CYP3A4 levels poses significant dangers. Without proper metabolism, these drugs remain in the body until CYP3A4 returns to normal functioning. It is essential to recognize this potential risk, as it can lead to adverse health effects and overdose.
Consulting a Healthcare Professional
Given the potential interactions between Delta 8 THC and prescription medications, it is crucial to consult with a healthcare professional before incorporating Delta 8 THC into your regimen. They can provide personalized guidance based on your specific medications and health condition. It is essential to ensure the safe and effective use of prescription drugs and delta-8 THC products.
This article was written by a cannabinoid specialist at DRIP Cannabinoids. DRIP Cannabinoids joined the market in June 2020. We quickly established our mission: providing customers with the purest oil on the market, and in tandem providing a premium product. Our products range from delta 8 oil, delta 8 pre-rolls, and 200 mg delta 8 gummies. Through each and every one of our products, DRIP strives to relieve people from the discomfort, stress, and anxiety of daily life by giving them access to cutting-edge cannabinoids such as Delta-10 and Delta-8 THC. DRIP’s formulas and procedures are all designed with the purity and safety of the customer in mind.
